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Shingu, K
Major cardiovascular event risk reduction that matters Wegovy is the only GLP-1 RA indicated for weight loss proven to help prevent life-threatening CV events for adults with established CVD and either overweight or obesity, along with diet and exercise 1,4,5 BMI, body mass index
Comprehensive assessments should also include screening for pregnancy where relevant, eating disorders, renal function, HbA1c (especially if diabetic or at risk), lipid profile, thyroid function, gallbladder/pancreatitis history, and potential drug interactions
Combination therapy with sCT and liraglutide mimicked the body weight-suppression achieved with liraglutide alone, resulting in a stronger and longer-lasting body weight change during the 3 rd and 4 th weeks of treatment
As body weight decreases, calorie needs often change, and the body may adapt to a lower weight over time
While tirzepatides use for weight loss may be considered off-label unless specifically approved by the FDA (such as under the brand name Zepbound), it is becoming an increasingly popular option for medically supervised weight management
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